TFIIIC90 Antibody

• Background:

  Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

• NCBI Gene ID:

  9329

• Swiss Prot:

  Q9UKN8

• Accession Number:

  Q9UKN8

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This TFIIIC90 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-244 amino acids from the N-terminal region of human TFIIIC90.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  92 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GTF3C4

• NCBI Official Name:

  General transcription factor 3C polypeptide 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Joubert, B.R., et al. Genome Med (3), 17 (2010) :

• Background Reference 02:

  Dumay-Odelot, H., et al. J. Biol. Chem. 282 (23) :17179-17189 (2007)

• Background Reference 03:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 04:

  Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

• Other Product Names:

  General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta, GTF3C4

• Tested Applications:

  WB, Flow

• Protein ID:

  212276467

• Physical Properties:

  Liquid