WTIP Antibody

• Background:

  WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity) .

• NCBI Gene ID:

  126374

• Swiss Prot:

  A6NIX2

• Accession Number:

  A6NIX2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This WTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids of human WTIP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  WTIP

• NCBI Official Name:

  Wilms tumor protein 1-interacting protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Wilms tumor protein 1-interacting protein, WT1-interacting protein, WTIP

• Tested Applications:

  WB, IHC-P, IF

• Physical Properties:

  Liquid