SOX1 Antibody

• Background:

  This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.

• NCBI Gene ID:

  6656

• Swiss Prot:

  O00570

• Accession Number:

  O00570

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human SOX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Monkey, Mouse, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SOX1

• NCBI Official Name:

  Transcription factor SOX-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Panayi, H., et al. J. Neurosci. 30 (37) :12274-12280 (2010)

• Background Reference 02:

  Phi, J.H., et al.Neurosurg Pediatr 5 (6) :608-614 (2010)

• Background Reference 03:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 04:

  Titulaer, M.J., et al. J. Clin. Oncol. 27 (26) :4260-4267 (2009)

• Other Product Names:

  Transcription factor SOX-1, SOX1

• Tested Applications:

  WB, Flow

• Physical Properties:

  Liquid