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OTX2 Antibody

CAT: 0223-55-983Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-983Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
NCBI Gene ID
5015
Swiss Prot
P32243
Accession Number
P32243
Host
Rabbit
Reactivity
Human
Immunogen
This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Symbol
OTX2
NCBI Official Name
Homeobox protein OTX2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Masuda, T., et al. J. Biol. Chem. 285 (35) :26933-26944 (2010)
Background Reference 03
Gonzalez-Rodriguez, J., et al. BrOphthalmol 94 (8) :1100-1104 (2010)
Background Reference 04
Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :
Other Product Names
Homeobox protein OTX2, Orthodenticle homolog 2, OTX2
Tested Applications
WB
Physical Properties
Liquid

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