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GALNS Antibody

CAT: 0223-55-960Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-960Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq].
NCBI Gene ID
2588
Swiss Prot
P34059
Accession Number
P34059
Host
Rabbit
Reactivity
Human
Immunogen
This GALNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human GALNS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Symbol
GALNS
NCBI Official Name
N-acetylgalactosamine-6-sulfatase
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Bank, R.A., et al. Mol. Genet. Metab. 97 (3) :196-201 (2009)
Background Reference 03
Yan, S., et al. Biopolymers 92 (5) :399-404 (2009)
Background Reference 04
Carraresi, L., et al. Clin. Chim. Acta 397 (1-2), 72-76 (2008) :
Other Product Names
N-acetylgalactosamine-6-sulfatase, Chondroitinsulfatase, Chondroitinase, Galactose-6-sulfate sulfatase, GalN6S, N-acetylgalactosamine-6-sulfate sulfatase, GalNAc6S sulfatase, GALNS
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
462148
Physical Properties
Liquid

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CSB-PA009202GA01HUGALNS Antibody

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