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UGT8 antibody

CAT: 0223-55-954Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-954Size:400 µL
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Background
Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45) . The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM].
NCBI Gene ID
7368
Swiss Prot
Q16880
Accession Number
Q16880
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This UGT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the Central region of human UGT8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
UGT8
NCBI Official Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Dziecedil Giel, P., et al. Br. J. Cancer 103 (4) :524-531 (2010)
Background Reference 02
Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)
Background Reference 03
Ross, C.J., et al. Nat. Genet. 41 (12) :1345-1349 (2009)
Background Reference 04
Ruckhaberle, E., et al. J. Cancer Res. Clin. Oncol. 135 (8) :1005-1013 (2009)
Other Product Names
2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase, UGT8, CGT, UGT4
Tested Applications
WB, IHC-P
Protein ID
296434442
Physical Properties
Liquid

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