KILLIN Antibody

• Background:

  DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.

• NCBI Gene ID:

  100144748

• Swiss Prot:

  B2CW77

• Accession Number:

  B2CW77

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  20 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KLLN

• NCBI Official Name:

  Killin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cho, Y.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (14) :5396-5401 (2008)

• Other Product Names:

  Killin, KLLN

• Tested Applications:

  WB

• Physical Properties:

  Liquid