MAML1 Antibody

CAT: 0223-55-913Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-913Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
NCBI Gene ID
9794
Swiss Prot
Q92585
Accession Number
Q92585
Host
Rabbit
Reactivity
Human
Immunogen
This MAML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human MAML1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Symbol
MAML1
NCBI Official Name
Mastermind-like protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Lindberg, M.J., et al. FASEB J. 24 (7) :2396-2404 (2010)
Background Reference 03
Hao, L., et al. Oncogene 29 (2) :201-213 (2010)
Background Reference 04
Saint Just Ribeiro, M., et al. Curr. Protein Pept. Sci. 10 (6) :570-576 (2009)
Other Product Names
HGNC:13632
Tested Applications
WB, Flow
Protein ID
68565602
Physical Properties
Liquid

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