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NTHL1 Antibody

CAT: 0223-55-909Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-909Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
NCBI Gene ID
4913
Swiss Prot
P78549
Accession Number
P78549
Host
Rabbit
Reactivity
Human
Immunogen
This NTHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human NTHL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NTHL1
NCBI Official Name
Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183}
NCBI Organism
Homo sapiens
Background Reference 01
Wang, W., et al. Nucleic Acids Res. (2010) In press :
Background Reference 02
Arora, M., et al. Leukemia 24 (8) :1470-1475 (2010)
Background Reference 03
Thyagarajan, B., et al. Biol. Blood Marrow Transplant. 16 (8) :1084-1089 (2010)
Background Reference 04
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Other Product Names
Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183}, hNTH1, 322- {ECO:0000255|HAMAP-Rule:MF_03183}, 429918 {ECO:0000255|HAMAP-Rule:MF_03183}, Bifunctional DNA N-glycoslyase/DNA- (apurinic or apyrimidinic site) lyase {ECO:0000255|HAMAP-Rule:MF_03183}, DNA glycoslyase/AP lyase {ECO:0000255|HAMAP-Rule:MF_03183}, NTHL1 {ECO:0000255|HAMAP-Rule:MF_03183}, NTH1, OCTS3
Tested Applications
WB
Protein ID
29840795
Physical Properties
Liquid

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