NTHL1 Antibody

• Background:

  The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.

• NCBI Gene ID:

  4913

• Swiss Prot:

  P78549

• Accession Number:

  P78549

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NTHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human NTHL1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  34 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NTHL1

• NCBI Official Name:

  Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, W., et al. Nucleic Acids Res. (2010) In press :

• Background Reference 02:

  Arora, M., et al. Leukemia 24 (8) :1470-1475 (2010)

• Background Reference 03:

  Thyagarajan, B., et al. Biol. Blood Marrow Transplant. 16 (8) :1084-1089 (2010)

• Background Reference 04:

  Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)

• Other Product Names:

  Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183}, hNTH1, 322- {ECO:0000255|HAMAP-Rule:MF_03183}, 429918 {ECO:0000255|HAMAP-Rule:MF_03183}, Bifunctional DNA N-glycoslyase/DNA- (apurinic or apyrimidinic site) lyase {ECO:0000255|HAMAP-Rule:MF_03183}, DNA glycoslyase/AP lyase {ECO:0000255|HAMAP-Rule:MF_03183}, NTHL1 {ECO:0000255|HAMAP-Rule:MF_03183}, NTH1, OCTS3

• Tested Applications:

  WB

• Protein ID:

  29840795

• Physical Properties:

  Liquid