HOXD13 Antibody

• Background:

  This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.

• NCBI Gene ID:

  3239

• Swiss Prot:

  P35453

• Accession Number:

  P35453

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This HOXD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human HOXD13.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  HOXD13

• NCBI Official Name:

  Homeobox protein Hox-D13

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sugie, Y., et al. Brain Dev. 32 (5) :356-361 (2010)

• Background Reference 02:

  Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

• Background Reference 03:

  Salsi, V., et al. Mol. Cell. Biol. 29 (21) :5775-5788 (2009)

• Background Reference 04:

  Cantile, M., et al. Int. J. Cancer 125 (7) :1532-1541 (2009)

• Other Product Names:

  Homeobox protein Hox-D13, Homeobox protein Hox-4I, HOXD13, HOX4I

• Tested Applications:

  WB

• Protein ID:

  223590221

• Physical Properties:

  Liquid