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GFER Antibody

CAT: 0223-55-699Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-699Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS) . The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1) . The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.
NCBI Gene ID
2671
Swiss Prot
P55789
Accession Number
P55789
Host
Rabbit
Reactivity
Human
Immunogen
This GFER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the Central region of human GFER.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GFER
NCBI Official Name
FAD-linked sulfhydryl oxidase ALR
NCBI Organism
Homo sapiens
Background Reference 01
Dong, L.Y., et al. Biochem. J. 431 (2) :277-287 (2010) Li, W., et al. FEBS Lett. 584 (18) :3929-3935 (2010) Daithankar, V.N., et al. Biochemistry 49 (31) :6737-6745 (2010) Dayoub, R., et al. Biochem. Biophys. Res. Commun. 395 (4) :465-470 (2010) Chang, J., et al. World J. Gastroenterol. 16 (2) :193-200 (2010)
Other Product Names
FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin, GFER, ALR, HERV1, HPO
Tested Applications
WB
Protein ID
218511915
Physical Properties
Liquid

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