GFER Antibody

• Background:

  The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS) . The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1) . The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.

• NCBI Gene ID:

  2671

• Swiss Prot:

  P55789

• Accession Number:

  P55789

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GFER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the Central region of human GFER.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GFER

• NCBI Official Name:

  FAD-linked sulfhydryl oxidase ALR

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dong, L.Y., et al. Biochem. J. 431 (2) :277-287 (2010) Li, W., et al. FEBS Lett. 584 (18) :3929-3935 (2010) Daithankar, V.N., et al. Biochemistry 49 (31) :6737-6745 (2010) Dayoub, R., et al. Biochem. Biophys. Res. Commun. 395 (4) :465-470 (2010) Chang, J., et al. World J. Gastroenterol. 16 (2) :193-200 (2010)

• Other Product Names:

  FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin, GFER, ALR, HERV1, HPO

• Tested Applications:

  WB

• Protein ID:

  218511915

• Physical Properties:

  Liquid