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GCH1 Antibody

CAT: 0223-46-847Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-46-847Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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NCBI Gene ID
2643
Swiss Prot
P30793
Accession Number
NP_000152.1, NP_001019195.1, NP_001019241.1, NP_001019242.1
Host
Goat
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-GKVHIGYLPNKQ
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Neuroscience
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Positive Control
Cat. No. 1314 - Human Thymus Tissue Lysate
Concentration
500 ug/mL
Homology
Expected Species Reactivity based on sequence homology: Mouse, Rat
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and store at -20˚ C. Minimize freezing and thawing.
Specificity
This antibody is expected to recognize all four isoforms (NP_000152.1 ; NP_001019195.1 ; NP_001019241.1 ; NP_001019242.1)
Applications Notes
Peptide ELISA: Western Blot:Immunohistochemistry:
Symbol
GCH1
Positive Control 2
Cat. No. 1315 - Human Tonsil Tissue Lysate
Positive Control 3
Cat. No. 1369 - Human Lymph node Tissue Lysate
NCBI Official Name
GTP cyclohydrolase 1
NCBI Organism
Homo sapiens
Background Reference 01
Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lotsch J, Fillingim RB, Maixner W, Geiss GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006 Nov;12 (11) :1269-77. Epub 2006 Oct 22.
Other Product Names
GCH1 , GTP cyclohydrolase 1 (dopa-responsive dystonia), DYT5, GCH, GTP-CH-1, GTPCH1, GTP cyclohydrolase 1, guanosine 5'-triphosphate cyclohydrolase I
Tested Applications
ELISA, WB, IHC
Protein ID
4503949
Physical Properties
Liquid

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