PTB Antibody

• NCBI Gene ID:

  19205 (mouse) ;29497 (rat)

• Swiss Prot:

  P17225

• Accession Number:

  NP_002810.1, NP_114367.1, NP_114368.1, NP_787041.1

• Host:

  Goat

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The immunogen for this antibody is: DGIVPDIAVGTKR-C

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  500 ug/mL

• Homology:

  Expected Species Reactivity based on sequence homology: Dog, Pig, Cow

• Buffer:

  Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. Minimize freezing and thawing.

• Specificity:

  This antibody is expected to recognise all 4 reported isoforms (represented by NP_002810.1; NP_114367.1; NP_114368.1; NP_787041.1) .

• Applications Notes:

  Peptide ELISA: Western Blot:Immunohistochemistry:

• Symbol:

  PTBP1

• NCBI Official Name:

  Polypyrimidine tract binding protein 1

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Charlet-B N, Logan P, Singh G, Cooper TA. Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Mol Cell. 2002 Mar;9 (3) :649-58.

• Other Product Names:

  PTBP1, PTB, polypyrimidine tract binding protein 1, PTB2, PTB3, PTB4, pPTB, HNRPI, PTB-1, HNRNPI, RNA binding protein, heterogeneous nuclear ribonucleoprotein polypeptide I, polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I), HNRNP-I, MGC10830, MGC8461, RNA-binding protein, heterogeneous nuclear ribonucleoprotein I

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4506243

• Physical Properties:

  Liquid