APH1A Antibody

• NCBI Gene ID:

  51107

• Swiss Prot:

  Q96BI3

• Accession Number:

  NP_001071096.1, NP_057106.2

• Host:

  Goat

• Reactivity:

  Human

• Immunogen:

  The immunogen for this antibody is: C-HVTDRSDARLQYG

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Positive Control:

  Cat. No. XBL-10106 - Human Cerebral Cortex Tissue Lysate

• Concentration:

  500 ug/mL

• Homology:

  Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow

• Buffer:

  Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. Minimize freezing and thawing.

• Specificity:

  This antibody is expected to recognize isoform 1 (NP_001071096.1) and isoform 2 (NP_057106.2) .

• Applications Notes:

  Peptide ELISA: Western Blot:Immunohistochemistry:

• Symbol:

  APH1A

• NCBI Official Name:

  APH1A gamma secretase subunit

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Spasic D, Raemaekers T, Dillen K, Declerck I, Baert V, Serneels L, Fullekrug J, Annaert W. Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway. J Cell Biol. 2007 Feb 26;176 (5) :629-40.

• Other Product Names:

  APH1A, anterior pharynx defective 1 homolog A (C. elegans), 6530402N02Rik, APH-1A, CGI-78 , anterior pharynx defective 1 homolog A

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  117606362

• Physical Properties:

  Liquid