PTRF 1 Antibody

CAT: 0223-39-859Size: 0.1 mgDry Ice: YesHazardous: No
CAT#:0223-39-859Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cavin 1-PTRF has been shown to be an essential component of caveolae. Cavin 1-PTRF appear to be recruited to membrane domains containing PS, cholesterol and oligomerized caveolins. Binding of Cavin 1-PTRF to these domains stabilizes the membrane curvature to produce the classic flask shape of caveolae. Disassembly of Cavin 1- PTRF releases caveolar components, including caveolins into the plasma membrane. Succinctly it appears that Cavin 1-PTRF regulates caveola structure and function.
NCBI Gene ID
284119
Swiss Prot
Q6NZI2
Accession Number
BAG60757
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the C terminal region.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
Affinity Purified
Concentration
Batch dependent
Modification
None
Shipping Conditions
Dry Ice
Fragment
IgG
Applications Notes
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Symbol
PTRF
NCBI Official Name
Polymerase I and transcript release factor
NCBI Organism
Homo sapiens
Background Reference 01
Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VM, Martin S, Hancock JF, Parton RG., PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function., Cell. 2008 Jan 11;132 (1) :23-4
Other Product Names
2310075E07Rik, AW546441, Cavin, MGC118550, Cavin 1, CAVIN1, CGL4, FKSG13, FLJ90031, OTTMUSP00000002049, polymerase I and transcript release factor, RNA polymerase I and transcript release factor, RP23-279L23.6, TTF I interacting 12, CAVIN, cavin-1
Tested Applications
ELISA, WB, IHC
Protein ID
56749614
Physical Properties
Liquid

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