Galectin-1 Antibody

• Background:

  The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin 1 may act as an autocrine negative growth factor that regulates cell proliferation. It also may regulate cell apoptosis and cell differentiation. It binds beta-galactoside, CD45, CD3 and CD4. Galectin 1 inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. It is found in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney, placenta and hematopoietic cells.

• NCBI Gene ID:

  3956

• Swiss Prot:

  P09382

• Accession Number:

  P09382

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hGalectin-1. Human Galectin-1 specific antibody was purified by affinity chromatography employing immobilized hGalectin-1 matrix.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Antibody Pairs

• Field of Research:

  Apoptosis

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Galectin-1 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  LGALS1

• NCBI Official Name:

  Lectin, galactoside-binding, soluble, 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GBP, GAL1Galectin-1, 14 kDa laminin-binding protein, Gal-1

• Tested Applications:

  ELISA, WB

• Protein ID:

  126155

• Physical Properties:

  Lyophilized