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PIDD Antibody

CAT: 0223-36-329Size: 50 µgDry Ice: NoHazardous: No
CAT#:0223-36-329Size:50 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
NCBI Gene ID
55367
Swiss Prot
Q9HB75
Accession Number
116242715
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant human PIDD (Death Domain: aa 776-910) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Innate Immunity
Concentration
1 mg/ml
Buffer
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Specificity
Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot.
Applications Notes
Immunohistochemistry: (paraffin sections) . Immunoprecipitation: (1:100) . Western Blot: (1:500) .
Symbol
PIDD1
NCBI Official Name
P53-induced death domain protein 1
NCBI Organism
Homo sapiens
Other Product Names
P53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd
Tested Applications
IHC, IP, WB
Protein ID
Q9HB75
Physical Properties
Liquid

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