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TNIP1 Antibody

CAT: 0223-55-570Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-570Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity) . Increases cell surface CD4 (T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
NCBI Gene ID
10318
Swiss Prot
Q15025
Accession Number
Q15025
Host
Rabbit
Reactivity
Human
Immunogen
This TNIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human TNIP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Symbol
TNIP1
NCBI Official Name
TNFAIP3-interacting protein 1
NCBI Organism
Homo sapiens
Background Reference 01
He, C.F., et al. Lupus 19 (10) :1181-1186 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)
Background Reference 04
Gateva, V., et al. Nat. Genet. 41 (11) :1228-1233 (2009)
Other Product Names
TNFAIP3-interacting protein 1, A20-binding inhibitor of NF-kappa-B activation 1, ABIN-1, HIV-1 Nef-interacting protein, Nef-associated factor 1, Naf1, Nip40-1, Virion-associated nuclear shuttling protein, VAN, hVAN, TNIP1, KIAA0113, NAF1
Tested Applications
WB, IHC-P
Protein ID
20138952
Physical Properties
Liquid

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