UPP2 Antibody

• Background:

  Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2 (') -deoxyuridine as substrates.

• NCBI Gene ID:

  151531

• Swiss Prot:

  O95045

• Accession Number:

  O95045

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This UPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  UPP2

• NCBI Official Name:

  Uridine phosphorylase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Maestrini, E., et al. Mol. Psychiatry 15 (9) :954-968 (2010)

• Background Reference 02:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 03:

  Johansson, M. Biochem. Biophys. Res. Commun. 307 (1) :41-46 (2003)

• Background Reference 04:

  Russell, R.L., et al. J. Biol. Chem. 276 (16) :13302-13307 (2001)

• Other Product Names:

  Uridine phosphorylase 2, UPase 2, UrdPase 2, UPP2

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid