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UPP2 Antibody

CAT: 0223-55-545Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-545Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2 (') -deoxyuridine as substrates.
NCBI Gene ID
151531
Swiss Prot
O95045
Accession Number
O95045
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This UPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Symbol
UPP2
NCBI Official Name
Uridine phosphorylase 2
NCBI Organism
Homo sapiens
Background Reference 01
Maestrini, E., et al. Mol. Psychiatry 15 (9) :954-968 (2010)
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Johansson, M. Biochem. Biophys. Res. Commun. 307 (1) :41-46 (2003)
Background Reference 04
Russell, R.L., et al. J. Biol. Chem. 276 (16) :13302-13307 (2001)
Other Product Names
Uridine phosphorylase 2, UPase 2, UrdPase 2, UPP2
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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