ASCL2 Antibody

CAT: 0223-55-538Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-538Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
NCBI Gene ID
430
Swiss Prot
Q99929
Accession Number
Q99929
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human ASCL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Xenopus, Bovine, Zebrafish
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ASCL2
NCBI Official Name
Achaete-scute homolog 2
NCBI Organism
Homo sapiens
Background Reference 01
Stange, D.E., et al. Gut 59 (9) :1236-1244 (2010)
Background Reference 02
Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)
Background Reference 03
Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)
Background Reference 04
Shahib, M.N., et al.Reprod Med 51 (11) :892-896 (2006)
Other Product Names
Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2, ASCL2, BHLHA45, HASH2
Tested Applications
WB
Protein ID
12644476
Physical Properties
Liquid

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