ASCL2 Antibody

• Background:

  This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.

• NCBI Gene ID:

  430

• Swiss Prot:

  Q99929

• Accession Number:

  Q99929

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human ASCL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat, Xenopus, Bovine, Zebrafish

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  20 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ASCL2

• NCBI Official Name:

  Achaete-scute homolog 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Stange, D.E., et al. Gut 59 (9) :1236-1244 (2010)

• Background Reference 02:

  Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)

• Background Reference 03:

  Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)

• Background Reference 04:

  Shahib, M.N., et al.Reprod Med 51 (11) :892-896 (2006)

• Other Product Names:

  Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2, ASCL2, BHLHA45, HASH2

• Tested Applications:

  WB

• Protein ID:

  12644476

• Physical Properties:

  Liquid