SP8 Antibody

• Background:

  Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity) .

• NCBI Gene ID:

  221833

• Swiss Prot:

  Q8IXZ3

• Accession Number:

  Q8IXZ3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This SP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SP8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  49 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SP8

• NCBI Official Name:

  Transcription factor Sp8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, M.T., et al. Mol. Psychiatry (2010) In press :

• Background Reference 02:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 03:

  Barber, M.J., et al. PLoS ONE (3), E9763 (2010) :

• Background Reference 04:

  Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)

• Other Product Names:

  Transcription factor Sp8, Specificity protein 8, SP8

• Tested Applications:

  WB

• Protein ID:

  300669678

• Physical Properties:

  Liquid