SP8 Antibody

• Background :

  Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity) .

• NCBI Gene ID :

  221833

• Swiss Prot :

  Q8IXZ3

• Accession Number :

  Q8IXZ3

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This SP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SP8.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Xenopus

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  49 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  SP8

• NCBI Official Name :

  Transcription factor Sp8

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lee, M.T., et al. Mol. Psychiatry (2010) In press :

• Background Reference 02 :

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 03 :

  Barber, M.J., et al. PLoS ONE (3), E9763 (2010) :

• Background Reference 04 :

  Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)

• Other Product Names :

  Transcription factor Sp8, Specificity protein 8, SP8

• Tested Applications :

  WB

• Protein ID :

  300669678

• Physical Properties :

  Liquid