MTX2 Antibody

• Background:

  The protein encoded by this gene is highly similar to the metaxin 2 protein from mouse, which has been shown to interact with the mitochondrial membrane protein metaxin 1. Because of this similarity, it is thought that the encoded protein is peripherally associated with the cytosolic face of the outer mitochondrial membrane, and that it is involved in the import of proteins into the mitochondrion. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7.

• NCBI Gene ID:

  10651

• Swiss Prot:

  O75431

• Accession Number:

  O75431

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human MTX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  30 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MTX2

• NCBI Official Name:

  Metaxin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Xie, J., et al. FEBS Lett. 581 (18) :3545-3549 (2007)

• Background Reference 03:

  Kozjak-Pavlovic, V., et al. EMBO Rep. 8 (6) :576-582 (2007)

• Background Reference 04:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names:

  Metaxin-2, Mitochondrial outer membrane import complex protein 2, MTX2

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid