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SACA1 Antibody

CAT: 0223-55-410Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-410Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
NCBI Gene ID
81833
Swiss Prot
Q9HBV2
Accession Number
Q9HBV2
Host
Rabbit
Reactivity
Human
Immunogen
This SACA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human SACA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Symbol
SPACA1
NCBI Official Name
Sperm acrosome membrane-associated protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Background Reference 02
Levy, D., et al. BMC Med. Genet.SUPPL 1, S3 (2007) :
Background Reference 03
Vasan, R.S., et al. BMC Med. Genet.SUPPL 1, S2 (2007) :
Background Reference 04
Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)
Other Product Names
Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32, SPACA1, SAMP32
Tested Applications
WB, IHC-P, Flow
Protein ID
74752784
Physical Properties
Liquid

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MBS6008413-01Rabbit anti-Human SACA1, NT
041379SACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32)
MBS6344852-01SACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32) (MaxLight 750)
MBS6344849-01SACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32) (MaxLight 490)
041379-BiotinSACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32) (Biotin)
041379-PESACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32) (PE)
041379-FITCSACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32) (FITC)

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