GNMT Antibody

• Background :

  Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.

• NCBI Gene ID :

  27232

• Swiss Prot :

  Q14749

• Accession Number :

  Q14749

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  33 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GNMT

• NCBI Official Name :

  Glycine N-methyltransferase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Augoustides-Savvopoulou, P., et al., J. Inherit. Metab. Dis. 26 (8) :745-759 (2003) . Tseng, T.L., et al., Cancer Res. 63 (3) :647-654 (2003) . Luka, Z., et al., Hum. Genet. 110 (1) :68-74 (2002) . Strausberg RL, et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) . Mudd, S.H., et al., J. Inherit. Metab. Dis. 24 (4) :448-464 (2001) .

• Other Product Names :

  Glycine N-methyltransferase, GNMT

• Tested Applications :

  WB

• Protein ID :

  12644416

• Physical Properties :

  Liquid