OAZ2 Antibody

• Background:

  Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].

• NCBI Gene ID:

  4947

• Swiss Prot:

  O95190

• Accession Number:

  O95190

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This OAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-151 amino acids from the C-terminal region of human OAZ2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  21 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  OAZ2

• NCBI Official Name:

  Ornithine decarboxylase antizyme 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Geerts, D., et al. Int. J. Cancer 126 (9) :2012-2024 (2010)

• Background Reference 02:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Background Reference 03:

  Mangold, U., et al. Biochem. J. 385 (PT 1), 21-28 (2005) :

• Background Reference 04:

  Chen, H., et al. J. Biol. Chem. 277 (48) :45957-45961 (2002)

• Other Product Names:

  Ornithine decarboxylase antizyme 2, AZ2, ODC-Az 2, OAZ2

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid