EHMT1 Antibody

• Background :

  EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

• NCBI Gene ID :

  79813

• Swiss Prot :

  Q9H9B1

• Accession Number :

  Q9H9B1

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This EHMT1 (EUHMTASE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 979-1010 amino acids from the Central region of human EHMT1 (EUHMTASE1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  141 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  EHMT1

• NCBI Official Name :

  Histone-lysine N-methyltransferase EHMT1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ogawa, H., et al., Science 296 (5570) :1132-1136 (2002) .

• Other Product Names :

  Histone-lysine N-methyltransferase EHMT1, 211-, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Lysine N-methyltransferase 1D, EHMT1, EUHMTASE1, GLP, KIAA1876, KMT1D

• Tested Applications :

  WB

• Protein ID :

  325511404

• Physical Properties :

  Liquid