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TMLHE Antibody

CAT: 0223-55-385Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-385Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
55217
Swiss Prot
Q9NVH6
Accession Number
Q9NVH6
Host
Rabbit
Reactivity
Human
Immunogen
This TMLHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the N-terminal region of human TMLHE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TMLHE
NCBI Official Name
Trimethyllysine dioxygenase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Monfregola, J., et al. Gene 395 (1-2), 86-97 (2007) :
Background Reference 02
Monfregola, J., et al. J. Cell. Physiol. 204 (3) :839-847 (2005)
Background Reference 03
Vaz, F.M., et al. J. Biol. Chem. 276 (36) :33512-33517 (2001)
Background Reference 04
Rogner, U.C., et al. Genome Res. 6 (10) :922-934 (1996)
Other Product Names
Trimethyllysine dioxygenase, mitochondrial, Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, Epsilon-trimethyllysine hydroxylase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TML dioxygenase, TMLD, TMLHE, TMLH
Tested Applications
WB
Protein ID
21542295
Physical Properties
Liquid

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