GPAA1 Antibody

• Background:

  Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.

• NCBI Gene ID:

  8733

• Swiss Prot:

  O43292

• Accession Number:

  O43292

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GPAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-73 amino acids from the N-terminal region of human GPAA1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  68 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GPAA1

• NCBI Official Name:

  Glycosylphosphatidylinositol anchor attachment 1 protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jiang, W.W., et al. Mol. Cancer 6, 74 (2007) :

• Background Reference 02:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 03:

  Ho, J.C., et al. Int. J. Cancer 119 (6) :1330-1337 (2006)

• Background Reference 04:

  Vainauskas, S., et al. J. Biol. Chem. 280 (16) :16402-16409 (2005)

• Other Product Names:

  Glycosylphosphatidylinositol anchor attachment 1 protein, GPI anchor attachment protein 1, GAA1 protein homolog, hGAA1, GPAA1, GAA1

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid