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MCHR1 Antibody

CAT: 0223-55-342Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-342Size:400 µL
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Background
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
NCBI Gene ID
2847
Swiss Prot
Q99705
Accession Number
Q99705
Host
Rabbit
Reactivity
Human
Immunogen
This MCHR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-422 amino acids from the C-terminal region of human MCHR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
MCHR1
NCBI Official Name
Melanin-concentrating hormone receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Miyamoto-Matsubara, M., et al. Ann. N. Y. Acad. Sci. 1200, 112-119 (2010) :
Background Reference 02
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 03
Miller, C.L., et al. Schizophr. Res. 113 (2-3), 259-267 (2009) :
Background Reference 04
Gavalas, N.G., et al. Exp. Dermatol. 18 (5) :454-463 (2009)
Other Product Names
Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, MCH1R, MCHR, SLC-1, Somatostatin receptor-like protein, MCHR1, GPR24, SLC1
Tested Applications
WB, IHC-P, Flow
Protein ID
33860175
Physical Properties
Liquid

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