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CES2 Antibody

CAT: 0223-55-320Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-320Size:400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
NCBI Gene ID
8824
Swiss Prot
O00748
Accession Number
O00748
Host
Rabbit
Reactivity
Human
Immunogen
This CES2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human CES2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Symbol
CES2
NCBI Official Name
Cocaine esterase
NCBI Organism
Homo sapiens
Background Reference 01
Holmes, R.S., et al. Mamm. Genome 21 (9-10), 427-441 (2010) Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Howard, T.D., et al. Environ. Health Perspect. 118 (10) :1395-1399 (2010) Hatfield, M.J., et al. Br. J. Pharmacol. 160 (8) :1916-1928 (2010) Holmes, R.S., et al. Genetica 138 (7) :695-708 (2010)
Other Product Names
Cocaine esterase, Carboxylesterase 2, CE-2, hCE-2, Methylumbelliferyl-acetate deacetylase 2, CES2, ICE
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid

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