CES2 Antibody

• Background :

  CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

• NCBI Gene ID :

  8824

• Swiss Prot :

  O00748

• Accession Number :

  O00748

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CES2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human CES2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  62 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CES2

• NCBI Official Name :

  Cocaine esterase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Holmes, R.S., et al. Mamm. Genome 21 (9-10), 427-441 (2010) Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Howard, T.D., et al. Environ. Health Perspect. 118 (10) :1395-1399 (2010) Hatfield, M.J., et al. Br. J. Pharmacol. 160 (8) :1916-1928 (2010) Holmes, R.S., et al. Genetica 138 (7) :695-708 (2010)

• Other Product Names :

  Cocaine esterase, Carboxylesterase 2, CE-2, hCE-2, Methylumbelliferyl-acetate deacetylase 2, CES2, ICE

• Tested Applications :

  WB, IHC-P, Flow

• Physical Properties :

  Liquid