CES1 Antibody

• Background:

  This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

• NCBI Gene ID:

  1066

• Swiss Prot:

  P23141

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 287-566 of human CES1 (NP_001257.4) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 63kDa

• Fragment:

  IgG

• Symbol:

  CES1

• Positive Control 2:

  A-549

• Positive Control 3:

  U-937

• NCBI Official Name:

  Carboxylesterase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CES1, ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH, REH, CE-1, hCE-1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid