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5HT3E Antibody

CAT: 0223-55-244Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-244Size:400 µL
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Background
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
NCBI Gene ID
285242
Swiss Prot
A5X5Y0
Accession Number
A5X5Y0
Host
Rabbit
Reactivity
Human
Immunogen
This 5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human 5HT3E.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
HTR3E
NCBI Official Name
5-hydroxytryptamine receptor 3E
NCBI Organism
Homo sapiens
Background Reference 01
Walstab, J., et al. J. Biol. Chem. 285 (35) :26956-26965 (2010)
Background Reference 02
Hammer, C., et al. Pharmacogenomics 11 (7) :943-950 (2010)
Background Reference 03
Lennertz, L., et al. Eur Neuropsychopharmacol 20 (6) :414-420 (2010)
Background Reference 04
Goecke, T.W., et al. Acta Obstet Gynecol Scand 89 (1) :7-14 (2010)
Other Product Names
5-hydroxytryptamine receptor 3E, 5-HT3-E, 5-HT3E, Serotonin receptor 3E, HTR3E
Tested Applications
WB, Flow
Physical Properties
Liquid

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