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MCAF2 Antibody

CAT: 0223-55-228Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-228Size:400 µL
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Background
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable) .
NCBI Gene ID
80063
Swiss Prot
Q5U623
Accession Number
Q5U623
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human MCAF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Symbol
ATF7IP2
NCBI Official Name
Activating transcription factor 7-interacting protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Adkins, D.E., et al. Mol. Psychiatry (2010) In press :
Background Reference 02
Ichimura, T., et al. J. Biol. Chem. 280 (14) :13928-13935 (2005)
Other Product Names
Activating transcription factor 7-interacting protein 2, ATF7-interacting protein 2, MBD1-containing chromatin-associated factor 2, ATF7IP2, MCAF2
Tested Applications
WB, IHC-P, Flow
Protein ID
143352739
Physical Properties
Liquid

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