BCMO1 Antibody

• Background:

  Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta, beta-carotene into two retinal molecules.

• NCBI Gene ID:

  53630

• Swiss Prot:

  Q9HAY6

• Accession Number:

  Q9HAY6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BCMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the Central region of human BCMO1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  63 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  BCO1

• NCBI Official Name:

  Beta, beta-carotene 15,15'-monooxygenase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lietz, G., et al. Arch. Biochem. Biophys. 502 (1) :8-16 (2010)

• Background Reference 02:

  Kim, Y.S., et al. Biotechnol. Lett. 32 (6) :847-853 (2010)

• Background Reference 03:

  Dastani, Z., et al. Eur. J. Hum. Genet. 18 (3) :342-347 (2010)

• Background Reference 04:

  Perry, J.R., et al. Diabetologia 52 (10) :2117-2121 (2009)

• Other Product Names:

  HGNC:13815

• Tested Applications:

  WB

• Protein ID:

  41688803

• Physical Properties:

  Liquid