IGF2BP1 Antibody

• Background:

  IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  10642

• Swiss Prot:

  Q9NZI8

• Accession Number:

  Q9NZI8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This IGF2BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-534 amino acids from the C-terminal region of human IGF2BP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat, Zebrafish, Chicken, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  63 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IGF2BP1

• NCBI Official Name:

  Insulin-like growth factor 2 mRNA-binding protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rodriguez, S., et al. Growth Horm. IGF Res. 20 (4) :310-318 (2010)

• Background Reference 02:

  Pillas, D., et al. PLoS Genet. (2), E1000856 (2010) :

• Background Reference 03:

  Noubissi, F.K., et al. Cancer Res. 69 (22) :8572-8578 (2009)

• Background Reference 04:

  Zhou, Y., et al. Virology 393 (2) :210-220 (2009)

• Other Product Names:

  Insulin-like growth factor 2 mRNA-binding protein 1, IGF2 mRNA-binding protein 1, IMP-1, IMP1, Coding region determinant-binding protein, CRD-BP, IGF-II mRNA-binding protein 1, VICKZ family member 1, Zipcode-binding protein 1, ZBP-1, IGF2BP1, CRDBP, VICKZ1, ZBP1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  296434536

• Physical Properties:

  Liquid