IGF2BP2 Antibody

• Background:

  This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• NCBI Gene ID:

  10644

• Swiss Prot:

  Q9Y6M1

• Accession Number:

  Q9Y6M1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This IGF2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-556 amino acids from the C-terminal region of human IGF2BP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  66 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IGF2BP2

• NCBI Official Name:

  Insulin-like growth factor 2 mRNA-binding protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Pechlivanis, S., et al. Arterioscler. Thromb. Vasc. Biol. 30 (9) :1867-1872 (2010)

• Background Reference 03:

  Heni, M., et al. Diabetes (2010) In press :

• Background Reference 04:

  Rodriguez, S., et al. Growth Horm. IGF Res. 20 (4) :310-318 (2010)

• Other Product Names:

  Insulin-like growth factor 2 mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2, IGF2BP2, IMP2, VICKZ2

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  224471831

• Physical Properties:

  Liquid