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IGF2BP2 Antibody

CAT: 0223-55-046Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-046Size:400 µL
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Background
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
10644
Swiss Prot
Q9Y6M1
Accession Number
Q9Y6M1
Host
Rabbit
Reactivity
Human
Immunogen
This IGF2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-556 amino acids from the C-terminal region of human IGF2BP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
66 kDa
Fragment
Rabbit Ig
Symbol
IGF2BP2
NCBI Official Name
Insulin-like growth factor 2 mRNA-binding protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Pechlivanis, S., et al. Arterioscler. Thromb. Vasc. Biol. 30 (9) :1867-1872 (2010)
Background Reference 03
Heni, M., et al. Diabetes (2010) In press :
Background Reference 04
Rodriguez, S., et al. Growth Horm. IGF Res. 20 (4) :310-318 (2010)
Other Product Names
Insulin-like growth factor 2 mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2, IGF2BP2, IMP2, VICKZ2
Tested Applications
WB, IHC-P, Flow
Protein ID
224471831
Physical Properties
Liquid

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