IGF2BP3 Antibody

• Background:

  The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

• NCBI Gene ID:

  10643

• Swiss Prot:

  O00425

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IGF2BP3 (NP_006538.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 72kDa

• Fragment:

  IgG

• Symbol:

  IGF2BP3

• Positive Control 2:

  BxPC-3

• Positive Control 3:

  SGC-7901

• Positive Control 4:

  NIH/3T3

• Positive Control 5:

  293T

• Positive Control 6:

  HepG2

• NCBI Official Name:

  Insulin like growth factor 2 mRNA binding protein 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3, insulin-like growth factor 2 mRNA-binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, VICKZ family member 3, cancer/testis antigen 98

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid