LCOR Antibody

• Background :

  LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]) .

• NCBI Gene ID :

  84458

• Swiss Prot :

  Q96JN0

• Accession Number :

  Q96JN0

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This LCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human LCOR.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  47 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  LCOR

• NCBI Official Name :

  Ligand-dependent corepressor

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Palijan, A., et al. J. Biol. Chem. 284 (44) :30275-30287 (2009)

• Background Reference 03 :

  Palijan, A., et al. J. Biol. Chem. 284 (44) :30264-30274 (2009)

• Background Reference 04 :

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names :

  Ligand-dependent corepressor, LCoR, Mblk1-related protein 2, LCOR, KIAA1795, MLR2

• Tested Applications :

  WB

• Protein ID :

  108936028

• Physical Properties :

  Liquid