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ALX4 Antibody

CAT: 0223-55-158Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-158Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2) ; an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del (11) (p11p12), causes Potocki-Shaffer syndrome (PSS) ; a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq].
NCBI Gene ID
60529
Swiss Prot
Q9H161
Accession Number
Q9H161
Host
Rabbit
Reactivity
Human
Immunogen
This ALX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-275 amino acids from the Central region of human ALX4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Symbol
ALX4
NCBI Official Name
Homeobox protein aristaless-like 4
NCBI Organism
Homo sapiens
Background Reference 01
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 02
Tanzer, M., et al. PLoS ONE (2), E9061 (2010) :
Background Reference 03
Kayserili, H., et al. Hum. Mol. Genet. 18 (22) :4357-4366 (2009)
Background Reference 04
Chang, H., et al. J. Clin. Pathol. 62 (10) :908-914 (2009)
Other Product Names
Homeobox protein aristaless-like 4, ALX4, KIAA1788
Tested Applications
WB, Flow
Protein ID
254763249
Physical Properties
Liquid

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