SPTBN2 Antibody [SPTBN2/1582]

• Background:

  Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alphaII (fodrin alpha) and spectrin betaI (fodrin beta) are present in other somatic cells. SPTBN2/Spectrin betaIII is highly homologous to both spectrin betaI and spectrin betaII. SPTBN2 is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.

• NCBI Gene ID:

  6712

• Swiss Prot:

  O15020

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.

• Clonality:

  Monoclonal

• Clone:

  SPTBN2/1582

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2a, kappa

• Symbol:

  SPTBN2

• NCBI Official Name:

  Spectrin beta, non-erythrocytic 2

• NCBI Organism:

  Homo sapiens

• Tested Applications:

  IHC-P, Flow, IF, WB, ELISA

• Physical Properties:

  Liquid