Beta Catenin Antibody [6F9]

• Background:

  Beta Catenin is a dual function protein, regulating the coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. b-Catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. b-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]

• NCBI Gene ID:

  1499

• Swiss Prot:

  P35222

• Host:

  Mouse

• Reactivity:

  Human, Bovine, Dog, Chicken

• Immunogen:

  Chicken beta-Catenin was used as the immunogen for the b-Catenin antibody.

• Clonality:

  Monoclonal

• Clone:

  6F9

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Symbol:

  CTNNB1

• NCBI Official Name:

  Catenin (cadherin-associated protein), beta 1, 88kDa

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Catenin beta-1, Beta-catenin, CTNNB1, CTNNB

• Tested Applications:

  IHC-P, Flow, IF, WB

• Physical Properties:

  Liquid