Products for Research Use Only
RegisterLogin

CYLD Antibody

CAT: 0223-33-052Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-33-052Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
NCBI Gene ID
1540
Swiss Prot
Q9NQC7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Protein A affinity chromatography
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Fragment
IgG
Symbol
CYLD
NCBI Official Name
CYLD lysine 63 deubiquitinase
NCBI Organism
Homo sapiens
Tested Applications
WB
Physical Properties
Liquid

Related Products

CatalogName
45-444PCYLD Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody
15-580POMGNT2 Antibody

Alternative Products

CatalogName
FNab02142CYLD antibody

Popular Products