TRBP2 Antibody

• Background:

  TRBP2 (TAR (HIV-1) RNA binding protein 2), along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex) . As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.

• NCBI Gene ID:

  6895

• Swiss Prot:

  Q8WY33

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Primate

• Immunogen:

  A recombinant protein fragment within the C-terminal region of TRBP2 was used as the immunogen for this antibody.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Protein A Affinity Chromatography

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG

• Symbol:

  TARBP2

• NCBI Official Name:

  TAR (HIV-1) RNA binding protein 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP

• Tested Applications:

  WB

• Physical Properties:

  Liquid