Viperin Antibody

• Background:

  Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs) .

• NCBI Gene ID:

  91543

• Swiss Prot:

  Q8WXG1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Protein A affinity chromatography purified antibody

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG

• Symbol:

  RSAD2

• NCBI Official Name:

  Radical S-adenosyl methionine domain containing 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RSAD2, 2510004L01Rik, cig33, cig5, vig1

• Tested Applications:

  WB

• Physical Properties:

  Liquid