Products for Research Use Only
RegisterLogin

DENND1B Antibody

CAT: 0223-55-155Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-55-155Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Clathrin (see MIM 118955) -mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024) . Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]) .
NCBI Gene ID
163486
Swiss Prot
Q6P3S1
Accession Number
Q6P3S1
Host
Rabbit
Reactivity
Human
Immunogen
This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
DENND1B
NCBI Official Name
DENN domain-containing protein 1B
NCBI Organism
Homo sapiens
Background Reference 01
Marat, A.L., et al. J. Biol. Chem. 285 (14) :10627-10637 (2010)
Background Reference 02
Sleiman, P.M., et al. N. Engl. J. Med. 362 (1) :36-44 (2010)
Background Reference 03
Venter, J.C., et al. Science 291 (5507) :1304-1351 (2001)
Other Product Names
DENN domain-containing protein 1B, Connecdenn 2, Protein FAM31B, DENND1B, C1orf218, FAM31B
Tested Applications
WB, IHC-P, Flow
Protein ID
74749089
Physical Properties
Liquid

Related Products

CatalogName
55-123DENND5B Antibody
16-426DENND4A Antibody
42-719Dennd4c Antibody
26-798DENND2C Antibody
42-719PDennd4c Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody

Alternative Products

CatalogName
70R-7075DENND1B antibody

Popular Products