NOS1AP Antibody

CAT: 0223-55-115Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-115Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS) . This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
9722
Swiss Prot
O75052
Accession Number
O75052
Host
Rabbit
Reactivity
Human
Immunogen
This NOS1AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human NOS1AP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
NOS1AP
NCBI Official Name
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Lu, J., et al. Diabet. Med. 27 (9) :1074-1079 (2010)
Background Reference 03
Husted, J.A., et al. Schizophr. Res. 121 (1-3), 187-192 (2010) :
Background Reference 04
Tomas, M., et al. J. Am. Coll. Cardiol. 55 (24) :2745-2752 (2010)
Other Product Names
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, C-terminal PDZ ligand of neuronal nitric oxide synthase protein, Nitric oxide synthase 1 adaptor protein, NOS1AP, CAPON, KIAA0464
Tested Applications
WB, Flow
Physical Properties
Liquid

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