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GGTLC2 Antibody

CAT: 0223-55-092Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-092Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]) .[supplied by OMIM].
NCBI Gene ID
91227
Swiss Prot
Q14390
Accession Number
Q14390
Host
Rabbit
Reactivity
Human
Immunogen
This GGTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human GGTLC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
GGTLC2
NCBI Official Name
Gamma-glutamyltransferase light chain 2
NCBI Organism
Homo sapiens
Background Reference 01
Heisterkamp, N., et al. Hum. Genet. 123 (4) :321-332 (2008)
Background Reference 02
Dunham, I., et al. Nature 402 (6761) :489-495 (1999)
Background Reference 03
Kawasaki, K., et al. Genome Res. 7 (3) :250-261 (1997)
Background Reference 04
Leh, H., et al. FEBS Lett. 394 (3) :258-262 (1996)
Other Product Names
Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTLC2, GGTL4
Tested Applications
WB, IHC-P, Flow
Protein ID
294862536
Physical Properties
Liquid

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