FBXO2 Antibody

CAT: 0223-55-088Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-088Size:400 µL
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Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.
NCBI Gene ID
26232
Swiss Prot
Q9UK22
Accession Number
Q9UK22
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This FBXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-271 amino acids from the C-terminal region of human FBXO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
FBXO2
NCBI Official Name
F-box only protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Eom, C.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (17) :9803-9807 (2003) Ilyin, G.P., et al. Gene 296 (1-2), 11-20 (2002) Yoshida, Y., et al. Nature 418 (6896) :438-442 (2002) Winston, J.T., et al. Curr. Biol. 9 (20) :1180-1182 (1999) Cenciarelli, C., et al. Curr. Biol. 9 (20) :1177-1179 (1999)
Other Product Names
F-box only protein 2, FBXO2, FBX2
Tested Applications
WB, Flow
Protein ID
51338836
Physical Properties
Liquid

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