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FBXO32 Antibody

CAT: 0223-61-173Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-173Size:200 µL
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Background
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
NCBI Gene ID
114907
Swiss Prot
Q969P5
Accession Number
Q969P5
Host
Rabbit
Reactivity
Human
Immunogen
This FBXO32 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 17-49 amino acids from human FBXO32.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Stem Cell
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
IgG1
Applications Notes
For WB starting dilution is: 1:2000
Symbol
FBXO32
NCBI Official Name
F-box only protein 32
NCBI Organism
Homo sapiens
Background Reference 01
Bodine S.C., et al.Science 294:1704-1708 (2001) .
Background Reference 02
Sivertsen E.A., et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
Background Reference 03
Pescatori M., et al.Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
Background Reference 04
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Other Product Names
F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx, FBXO32
Tested Applications
WB
Protein ID
20177894
Physical Properties
Liquid

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