MAF1 Antibody

• Background :

  This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III) . It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.

• NCBI Gene ID :

  84232

• Swiss Prot :

  Q9H063

• Accession Number :

  Q9H063

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This MAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human MAF1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  29 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  MAF1

• NCBI Official Name :

  Repressor of RNA polymerase III transcription MAF1 homolog

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kantidakis, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (26) :11823-11828 (2010)

• Background Reference 02 :

  Shor, B., et al. J. Biol. Chem. 285 (20) :15380-15392 (2010)

• Background Reference 03 :

  Johnson, S.S., et al. Mol. Cell 26 (3) :367-379 (2007)

• Background Reference 04 :

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names :

  Repressor of RNA polymerase III transcription MAF1 homolog, MAF1

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  296434582

• Physical Properties :

  Liquid